Cornejo P, Petrova V, Zhang X, Young R, Wong ES. Enhancer turnover in cancer and species evolution are associated with DNA replication timing.
Achinger-Kawecka J, Stirzaker C, Chia K, Portman N, Campbell E, Du Q, Laven-Law G, Nair S, Yong A, Wilkinson A, Clifton S, Milioli H, Schmitt A, Wong ES, Hickey T, Lim E, Clark S. Epigenetic therapy suppresses endocrine-resistant breast tumour growth by re-wiring ER-mediated 3D chromatin interactions.
Marjaneh M, Kirk E, Patrick R, Alankerage D, Humphreys D, Del Monte-Nieto G, Janbandhu V, Cornejo P, Doan T, Dunwoodie S, Wong ES, Moran C, Martin I, Thomson P, Harvey R. Quantitative trait and transcriptome analysis of genetic complexity underpinning cardiac interatrial septation in mice using an advanced intercross line.
Cornejo P, Roper K, Degnan S, Degnan B, Wong ES (2022) Distal regulation, silencers and a shared combinatorial syntax are hallmarks of animal embryogenesis. Genome Research 32:474-487
Fennell KA, Vassiliadis D, Lam L, Martelotto LG, Balic J, Wang Q, Hollizeck S, Weber T, Semple T, Miles D, MacPherson L, Kat L, Wong ES, Dawson S, Naik S, Dawson MA (2022) Identifying non-genetic determinants of malignant clonal fitness at single cell resolution. Nature 601:125-131
Flochay S^, Wong ES^, Zhao B^, Viales R, Thomas-Cholier M, Thieffry D, Garfield D, Furlong E (2021) Cis-acting variation is common across regulatory layers but is often buffered in developmental programs Genome Research 31:211-224 [doi:10.1101/gr.266338.120] ^equal contributions
Wong ES, Zheng D, Tan S, Bower N, Garside V, Vanwalleghem G, Gaiti F, Scott E, Hogan B, Kikuchi K, McGlinn E, Francois M, Degnan B (2020) Deep conservation of the enhancer regulatory code in animals Science 370:6517 [doi: 10.1126/science.aax8137]
Friedman CE, …, Wong ES, .., Powell J, Palpant NJ (2018) Single cell transcriptomic analysis of cardiac differentiation from human PSCs reveals HOPX-dependent cardiomyocyte maturation Cell Stem Cell 23:586-598 [doi: 10.1016/j.stem.2018.09.009]
Jasinska AJ, … Wong ES, …, Freimer N (2017) Genetic variation and gene expression across multiple tissues and developmental stages in a non-human primate Nature Genetics 49:1714-1721 [doi: 10/1038/ng.3959]
Wong ES, Schmitt B, Thybert D, Marioni J, Ferguson-Smith A, Odom DS*, Flicek P* (2017) Interplay of cis and trans mechanisms driving transcription factor binding, chromatin, and gene expression evolution Nature Communications 8:1092 [doi: 10.1038/s41467-017-011037-x]
Wong ES, Thybert D, Schmitt B, Stefflova K, Odom DS*, Flicek P* (2015) Decoupling of evolutionary changes in transcription factor binding and gene expression in mammals Genome Research 25:167-78 [doi: 10.1101/gr.177840.114]